If you had one chance to eat or drink something poisonous without dying or experiencing any health repercussions, what would you try?

Joke's on you. I've been slowly building up an immunity to iocaine powder for years.

Clearly, you have a dizzying intellect.
- So I obviously cannot choose the wine in front of me.

A glass of mercury, it looks like it tastes delicious.

Sooo elemental mercury. Not absorbed well in the GI tract. I had a patient who took time cracking open thermometers from boilers for a while and then attempted to drink it mixed with some coffee to commit suicide. We show up since he called 911 and now wanted to go to the hospital. Call poison control for recommendations for local hospitals since this isn't common and i don't know what hospitals can handle this thing. Poison control cites that it isn't well absorbed, if at all, in the GI tract. I was pretty surprised.

So really you could drink it and find out the taste with very small if any repercussions.

Ya know, just saying.
- Didn't uh.. something like Lewis and Clarke..
  
  Didn't they use mercury based laxatives, and that was used to track their path?
  
  https://www.smithsonianmag.com/smart-news/how-reconstruct-lewis-and-clark-journey-follow-mercury-laden-latrine-pits-180956518/
- Yeah elemental mercury ain't that bad. It's all those organic compounds of mercury that are the baddies.
  
  And.... you know, shiny poops that hit the bottom of the bowl with a THUNK , that would be something different. You'd literally lose a few pounds every time you went to the toilet.
I’m curious how it feels to drink something that heavy
- I imagine afterwards you'd just sit and reflect.
Seems like it would sit pretty heavy, though...
- Nah, it goes down real smooth.
Cody's lab has entered the chat

Sitting down with a good movie and a bowl of tide pods.

You might be happy to know, my mouth literally dropped open when I read your comment 😂
- Dropped open to eat another tide pod

I mean... alcohol? You can already buy it easily prepared in all sorts of delicious ways.

Am I not in the spirit of the thing?

The effects is what makes it delicious, no effects means no upside to drinking the poison
- You haven't changed my mind, but now I'm mildly concerned about you and I'm here if you need help.

I want to lick The Elephant's Foot.

Does lava count as poisonous

8 kilos of molten gold.

I would see what the big deal with heroine is

Heroin*

Heroine is the feminine form of hero
- He said what he said!
If you don't experience any of the reprocussions, would it even do anything?
- You would probably get high but have the incredibly painful withdrawal symptoms.
  
  Granted, the euphoria alone would probably incentivize you to try it again anyway, so I still wouldn't

Fugu. I’m far too much of a coward to try it normally.

One of those poisonous dart frogs

Red paint. No. Blue paint. Which ever one smells better.

I heard some poisonous mushrooms are very tasty...

I mean you don't need invulnerability to find out, you just gotta choose wisely, since you only get one shot.

The fly agaric mushroom. I wanna see if it makes me taller.

You can eat those if you prepare them correctly. Prepare for a cozy experience if you dose it right. shroomery
Totally. Seem them everywhere, and they're so cute. Would be great to just munch them, buttered on toast...