The Nier series will continue as long as Yoko Taro remains alive, producer says

What do you mean? There’s like 10,000 (?) years of history between replicant and automata. There’s so much that could happen. They could lean hard into the cyclic timeline theme and have literally the same story set up as automata just have it play out completely differently. Maybe an origin story for the machine lifeforms. I don’t think a direct sequel will ever happen but there’s a lot in the nier universe to explore.