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Metformin may improve outcomes in patients with non-small cell lung cancer (NSCLC) who are overweight or obese, according to a study published in the Journal of the National Cancer Institute.

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Metformin May Improve RFS, OS in NSCLC Patients Who Are Overweight or Obese

The study showed that metformin use was associated with improvements in overall survival (OS) and recurrence-free survival (RFS) for overweight and obese patients who had undergone lobectomy. Researchers also found that metformin was associated with longer progression-free survival (PFS) in overweight NSCLC patients treated with immune checkpoint inhibitors (ICIs).

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