Unless there are reports of backdoors in Graphene OS I don't see a reason to not use it (well, YMMV if the developer's dialogue affects you - this is the internet bro). I get that Graphene is not the Degoogle expert in Android OS markets (\e\OS for you lot if you don't want to do manual work), but it can be degoogled the same way that Lineage can be degoogled - change the API calls to google servers. That's all of the Google influence these ROMs have.
This OS is fantastic and if I were to purchase a pixel I would use it. Absolutely