What cross are you talking about? Ankhs are the only thing that comes to mind and you buy those at the shops at the start of each 5 level set, so 6,11,16, etc. Ankhs provide a resurrection if you die but you won't have your gear or any potions etc, so you have to run back to the site at which you died where you will find a backpack with all your stuff.
Sometimes my dumbass pops 2 on the same floor because I refused to drink healing pots.
But yeah, I don't even bless them now. Seem like a waste of water. Always have them as a flex, and to be safe (although my +13 plate armor does a pretty good job helping me with that)