EDIT (2024-08-10T19:23Z): I should clarify that I am referring to the layout that you use for a physical computer keyboard, not a mobile/virtual keyboard.
I've tried Dvorak and Workman but switched to Colemak-DH about a year ago just for fun and to try something new (I have a split ortho keyboard with XDA keycaps so the profile is uniform).
Works great, but my typing speed dropped by about 40 WPM from the low 110s to the mid-70s and I haven't had enough time to practice and get back up there. Previous layouts have required at least a few months of practice with Monkeytype or Keybr and I've been too busy.
Also made a huge effort to switch to Colemak-DH a few months ago then started moving around a bunch with little space to setup my split ergo and will take a huge hit getting started again :/
Hmm, you know, I think I liked Workman the most. Colemak has been the most difficult to adapt to, but I'm not sure if it's because I had been away from QWERTY for so long (Colemak has a lot of keys in common with QWERTY) or because the layout has keys in locations that I don't find the most intuitive.
Honestly, if I'm still hovering around 80 WPM for much longer it might actually be a good move to switch back to Workman, lol. Dvorak was probably the best IMO for reducing finger and wrist movement and strain if that's a concern for you.
I personally went from QWERTY to Dvorak to Colemak to Workman. I probably stayed on Colemak for the least amount of time. I've been on Workman for quite a number of years, now.