11mo ago

TIL psychedelics supposedly work by desynchronizing the brain

www.nature.com

A psychedelic state arises from desynchronized brain activity

41 comments

Too bad the article is paywalled
- https://www.nature.com/articles/s41586-024-07624-5
  Try that
  
  Ah, I know some of these words
- It is. This seems to be an article about the study, which I think is in pre-print.
  https://www.npr.org/sections/shots-health-news/2024/07/18/g-s1-11501/psilocybin-psychedelic-drug-brain-plasticity-depression-addiction
Considering that autistic people have hyper connectivity within brain sections but hypo connectivity between them, I wonder if psychedelics hit them noticeably different from normies.
- Probably. Any Asperger’s kid around wanting to try some science?
  
  I'm here! I've done acid and shrooms several times. I can talk about my experiences, but I have no idea if others experience it similarly.
  Here's a trip simulator that I find is pretty close to the visual experience: https://youtu.be/3BxiYkCPZwI?si=dVD6sPpk7KdhFx3e
  
  I don't know that I'm autistic enough. Seemed to have a similar experience with both Shrooms and LSD as everyone else. I've only had one bad trip, and it was shrooms. A little Ativan and some company and I pulled through. It is usually a very happy, warm, and enlightening experience
  
  lol...
Tilting my bio-cartridge.
Does that mean we are living with vsync on?
- That’s what I feel. Like frames seem to get mixed together and I have to do a manual refresh. But this is also how I can build castles in the clouds.
It's not desyncronized. Just synchronized in a different way we're not used to.
- Semantics are hard.
  
  They're not hard, they're tough in a different way.
  
  To be honest I hope my comment helps people understand the nature of psychedelics. Think of it as tl:dr

41 comments