Maybe if you used VR Chat all the time, but there's vfio for those cases, if needed. I just learned about it from another user, and so there's really no need to keep Windows as your primary boot partition or even have a dual boot setup.
My Quest 2 has been running VR fine. ALVR's latest update made me finally nuke my Windows partition I kept for VR.
Other than Angry Birds VR needing to have the recenter button hit after it's first launched, so far it's been fine for HL: Alyx, Beat Saber, Budget Cuts, and a few others I've tried. Literally the only workaround quirk I've found so far.