I'm honestly surprised to have not seen Super Eyepatch Wolf show up yet. Because of him, I'll never look at Garfield the same way again. He might not put out content often, but as far as I've seen, it's all top notch quality.
Tokyo Lens is another I enjoy. Fun explorations of Japan, lots of cool informational stuff, stuff like that. A little bit Abroad in Japan, but somewhat less bombastically edited, and a bit more positive.
Clemps is another one that doesn't put out content very often, but does some great deep dives into older JRPGs, and some fantastic looks at Yoko Taro's games.
Then there's the ones that have been posted again and again: RedLetterMedia, Technology Connections, Tom Scott, Jacob Geller, Food Wishes, You Suck At Cooking. I'm sure there's more out there, and there will always be more new ones popping up, too.