Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised.
In medicine, finding out what doesn't work is nearly as valuable as finding what does. Because finding out why it doesn't work can lead to you the solution and perhaps even solutions for things you weren't even looking for.
UC Riverside has now been issued a US patent on this RNAi vaccine technology
Naturally, you'll want to patent it so you can profit off it instead of just releasing it to benefit all of humanity. Fucking greedy ass people sometimes...
I do t know UC Riverside’s history for how they manage their patents, but I’m on the side of giving them the benefit of the doubt until proven otherwise. It’s okay to have a patent. It’s ok to profit off an invention you spent a lot of money producing. But what’s not ok would be upping the price so high that people have to choose dying over getting the product because they simply can’t afford it. Let’s hope UC does the former and not the latter.
Generally these "patented" products from universities are funded via tax payer money. I am not cool with them profiting off something that is intended to save lives and was also funded by the very people who's lives will be affected.
Putting things behind a patent wall only hinders progress.
Just because it’s patented doesn’t mean it can’t still be released for the benefit of humanity. It does mean it will be harder for some for-profit entity to claim the process for themselves. This may be naive, but I feel like a public (state-owned) nonprofit research university will be a better steward for the patent than a private entity that’s seeking to maximize shareholder value. I would expect that they would either license the patent freely for humanitarian benefit or at a reasonable cost to support the university’s ongoing research efforts.
That's not how patents work. They have to guard it or else someone else will. You don't know the university's goals yet, but you would know the goal of a for profit pharma company.
It’s a fucking nonprofit. Without the royalty stream, shit like this can only be discovered, developed, and brought to market by big pharma. Then what happens?
"Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised. "
Paper says
"Live-attenuated virus vaccine defective in RNAi suppression induces rapid protection in neonatal and adult mice lacking mature B and T cells"
I love how they probably used chatgpt to summarize the article for their website. And jumping from here to saying "this vaccine is effective against everything ever" seems a bit! over reaching. Even universal vaccines within a given subtype are finicky. There seems to be a trade off between universality (of recognition) and of effectiveness. Nevertheless this seems like a different mechanism than previous RNA/protein vaccines in that it seems to work by inducing innate immunity. Even though they say that mice remain immune 90d post vaccination, that is another area where mice and men can be substantially different, so I think we are still at the wait and see stage unfortunately.
And this joke of a sentence here
"With one vaccine injection, they found the mice were protected from a lethal dose of the unmodified virus for at least 90 days. Note that some studies show nine mouse days are roughly equivalent to one human year. "
If you want to search for it yourself it's "Live-attenuated virus vaccine defective in RNAi suppression induces rapid protection in neonatal and adult mice lacking mature B and T cells" by Gang Chen, Qingxia Han, Wan-Xiang Li, and Shou-Wei Ding