My third year thermodynamics course opened with a similar quip by the lecturer. Entropy is actually depressing. You can't fight it. You can't not fight it. It just wins.
My favorite class in grad school. I absolutely loved deriving the laws of thermodynamics from first principles based the random motion of atoms. It was beautiful.
Yeah lol, lots of physics and math was invented by multidisciplinary geniuses who saw equations that seemed to have no answer and said "oh yeah, this looks like a problem from biology that I've seen solved with this bit of fluid mechanics, and that problem can be solved with this complex trick from differential calculus. And you know, after we do that the whole system is starting to look like a circuit that uses properties from thermodynamics..."
Then your teacher and the textbook throws it on a white board and says "some smart dude figured out this was the way to solve this problem. It looks like this and it boils down to this equation. Don't ask questions."
There's a mechanics textbook called "there once was a classical theory" and it opens with:
There once was a classical theory
Of which quantum disciples were leery.
They said, “Why spend so long
On a theory that’s wrong?”
Well, it works for your everyday query!
Meanwhile, a strong contender for the best opening line in fiction is: "There once was a boy named Eustace Clarence Scrubbs, and he almost deserved it."