The One that Shoots Hexagonal Bullets - Whitworth Rifle (1860)
Sir Joseph Whitworth is quite the famous name in engineering circles, credited with the development of such things as Whitworth threading (the first standardized thread pattern) and engineer’s blue. When he decided to make a rifle, he decided that he could make flat surfaces more precisely than round ones, and chose to design a rifle with a hexagonal bore and mechanically fitted bullets.
Well alleight then, from now on I'll call my hip group of engineers The Hexagon. You'll have to tell Jimbo that he's out, though, as he was the seventh member.
Looked up how to drill hexagonal holes and came up with some answers for holes that weren't much deeper than their width... Really not sure how this would be done for a rifle bore, though. Is there twist to the bore? Seems like a nightmare to manufacture.
Polygonal rifling is commonly found on nearly all Glock pistols along with many of Heckler & Koch's guns just to name two brands. I think technically the mechanics of the Whitworth rifling differentiate it from modern polygonal rifling, but that's me being very technical and pedantic.
Button rifling is common, but as I understand it the machines are pretty expensive, so it's the big players doing that, mostly. There's still plenty of traditional cut rifling too. IIRC, the cut rifling ends up with a better finish and doesn't get as much stress imparted to the steel.
Spinning helps with range and accuracy. How destructive a bullet is more because of its weight and speed, which is controlled by how much propellant like gunpowder.
Spinning "rifling" is what makes a bullet go straight. Before then, you'd just have to hope it hits in that general area you're aiming for. Any imbalance in weight would steer the bullet then.