What exactly do the different types of stage3 archive do?

I've heard that you should be using the appropriate stage3 archive for the profile you want to use, but what exactly are the differences between them? I'm asking this because I want to try doing a Hardened/SELinux/Musl/LLVM install, and there's a profile for that, but not the stage3 archive. I was thinking of starting with either Hardened/Musl or LLVM/Musl. Any thoughts on that?