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Is it possible for E and T levels to be fine but get zero results due to issues in your endocrine sustem

I've been wondering if the reason I've only seen small results after nearly two years is that while my levels are fine by body can't do what it's supposed to. And if that's the case should I just quit hrt

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10 comments
  • You aren't getting zero results. You are getting results, but can't see them accurately because that's how being raised in a transphobic society so often manifests for us when combined with mental health struggles

  • From my understanding how a body responds to HRT is basically down to luck. Changes can be large, small, fast and slow. The chances of seeing large changes might decrease over time but is probably never zero.

    One thing to note is that we are often our worst critics. We see all the things that haven't changed or things changed so gradually that we never noticed. These changes can be obvious to those around us while we remain blind to them.

    The question I would ask is do you want to continue taking HRT? Is it causing you an undue burden or harm? Will stopping make you feel better? Will stopping make you feel worse? These are probably things to discuss with a doctor to help you come to a decision.

  • You have been asking us if you should quit hrt for months now and our answers are always going to boil down to no you shouldn't. You honestly look fine imo and I think at this point you need to see a therapist because there's only so much random Internet people can do for you.

  • Sky, you talk yourself into so many terrible thoughts. You're always trying to puzzle out how to fit yourself into a terrible story you're in the midst of telling. This is the first time I've gone through your post history and dug up pictures. You're cute. I'm jealous of how god awful big your hair is. I see a lot of my neighborhood's trans people at work. I honestly expected much worse in your pictures. You should focus on building Sky the woman on the inside. Make yourself the person you want to be on the inside. Your body will inevitably follow your heart. Your ego will inevitably shape your form. More esoterically, there are only two things: the Goddess and the leviathan. Thankfully, the creature tends to obey her commands.

    I wish we knew each other in person instead of just on this hole in the wall website. You seem like the sort of troubled woman my wife gives me a hard time for constantly trying to befriend.

  • There are occasional forum posts with lab results by transwomen who suspect they may have an unstudied SHBG variation causing a preferential bond to the strong agonist E1 which some claim might generally result in a greater prevalence of the weaker agonist E2 being available to cell estrogen receptors. Some further speculate this claimed SHBG variation to be a possible causal mechanism for the three atypical sexual dimorphisms observed in the brains of transwomen.

    Generally such folks say they see better results following a switch from pills to injections and orchiectomy. Please take all of this with a grain of salt. However, it could be good idea to ask your doctor about getting your E1 and E2 levels checked.

    Why quit HRT? Those transwomen who came before us made due with far fewer options than we have today. A glass is not perfectly filled to just the right, perfect height or else unenjoyable!

  • We're all different. Cis women with equal levels of E also have wildly different features, it's not really something any of us can control outside surgery. It's your life, and your right to move through the world in whatever way makes you most comfortable, content and assured. Stopjng or continuing HRT is a choice that make you no more or less of a woman, I get the appeal of being free of the hassle of pills/shots but even if your progress is slower than you want it to be, I think letting T revert changes would be more upsetting than staying the course.

    But that's just my 2 cents Hon, you're still valid af and braver than most for walking down the HRT path in the first place. No matter what you decide, you are worthy of love and respect! ♥ 💕

  • I'm not sure there's been much research into it, it sounds like it could be plausible.

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