4w ago

People with social anxiety disorder have a different gut microbiome - transplanting their microbiome to mice causes the mice to suffer from increased social fear

www.pnas.org

Just a moment...

4w ago

www.pnas.org /doi/abs/10.1073/pnas.2308706120

Science @europe.pub

tfm @europe.pub

4w ago

Social anxiety disorder-associated gut microbiota increases social fear

www.pnas.org /doi/abs/10.1073/pnas.2308706120

32 comments

Whose shit do I need to eat to feel like a normal person?
- You can adjust your own gut bacteria in 3-9 months through diet alone. Eating shit is a unnecessary optimization.
  
  yeah, you don’t eat it. water, fecal sample, enemia. EZ
  or just eat some yogurt, kimchi, fruit and veggies.
  
  Go on..
- So that's what rimming is all about; they have anxiety. TIL.
I think a lot of people don't realise how much of what makes "them" them is gut biome and your brain retrospectively assigning yourself agency for actions your body decided on (flinching from hot surfaces is one).
We just keep finding more ways that gut bacteria influence our diet and behaviour. And if you obey your gut flora and eat sugar instead of protein, you'll allow them to increase which expands their influence over you. Or that part of you, since where's the line?
- Or that part of you, since where's the line?
  Brains exist in a chemical soup, but you are still you even if the soup changes. The good thing about this relationship is the brain can control the food and slowly change the gut and in turn the chemical soup the brain exists in.
- Not that extreme. But the brain has way more "wires" from than to the gut.
  And the "you" changes with every new experience, so there's that.
- Souls and people „don’t exist“. Because all that you and everyone thinks is you is just your brain taking inputs and making outputs by weighing all its available data. Gut is just another data source which influences your brains actions.
- i'm not sure how flinching from hot surfaces is an example of assigning oneself agency, i've never heard anyone say "yeah i chose to pull my hand away because it was hot", everyone obviously knows that's a reflex lol
- Psychedelics can do more to the brain than the gut biome.
“Shut up or I’ll give you my anxiety” has now become a threat that is possible to follow through on.
- Yes technically, but… I was gonna say “how would you even act on that?” but decided I’d prefer not to know.
  
  As someone who does know how transplanting gut biome works... yea, you absolutely don't want to know.
  Just know that a "Stool Bank", which is a facility which holds samples of fecal matter tested to ensure no transferable disease, is a real thing that exists and is relevant to this discussion.
  
  Shit put into a pill that you swallow.
These researchers are bastards! Why didn't they transplant the gut microbiome from the mouse to the human instead, to cure the test patient's social anxiety?
- "well they cured my anxiety but now cats make me weep in fear and i have an addiction to cheese.."
Interesting stuff.
As a side note, I feel like a lot of people tend to erroneously conflate mostly normal social anxiety (e.g. feeling anxious when meeting new people) with SAD, which tends to be diagnosed when the anxiety is actually severe/crippling. Kind of like how PTSD or OCD are thrown around super casually these days.
So, I shit fear?
n = 6 (or n = 12)
Very interesting. But at best a potential fact that needs to be replicated in a large cohort. Don’t assume it’s a proven fact just from this study.
It's really weird but I seem to more easily get panic attacks if I haven't eaten yet that day. I wonder if this has something to do with it as well.
- Well everyone, even "normies", accepts that "hangry" is a thing. So it really shouldn't be surprising that our eating habits are so directly related to our mood and state of mind.
- i'd imagine that's more down to the simple fact of having readily available energy in your body, plus stuff like food being comforting.
Is this why I feel less anxious post shit

32 comments