It helps mixing 2d & 3d elements, for sure. I've also been playing with leaving details out on both the models and the textures. Since, in real life, it would be tedious to draw, for example, every leaf on a tree. A good amount of traditional art looks to either simplify these details or finding ways to trick the brain into filling them in by itself.
If I could figure out how to get my textures to also scale with distance a bit, by both shrinking and losing detail, it would sell the illusion even more!