ANCA vasculitis and IgA nephropathy linked to silica exposure
ANCA vasculitis and IgA nephropathy linked to silica exposure

ANCA vasculitis and IgA nephropathy linked to silica exposure

Key learning points
What is already known about this subject
Silica is known to be immunogenic and is associated with autoimmune diseases.
There is a known association between ANCA-associated vasculitis and silica exposure, although the exact mechanism of injury is not known.
There are only a few case reports describing the association of silica exposure and IgA nephropathy.
What this study adds
This is the first documented case report, to our knowledge, of co-existing ANCA-associated vasculitis and IgA nephropathy linked to hilar lymphadenopathy due to silica exposure.
This case highlights the relevance of occupation exposures in renal disease, and the immune-stimulatory effect of silica.