Interesting idea, because my boxer briefs support my balls in the middle, but my dress pants have one seam down the middle, so when I sit for prolonged periods I get a seam uncomfortably squishing my equipment. If instead the seam was always resting to one side or the other, I wouldn't have that problem. To fix this, we should either have underwear that better accommodates a middle seam, or my preference would be pants with a built in pouch similar to underwear. It would accentuate the "bulge", but we could get used to that.
I often use underwear that have a bigger and better formed pouch to provide a more natural fit instead of just beating it to compliance like normal underwear does. It's so much more comfortable.