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It's mostly true. Someone coming from windows may struggle with gnome, while cinnamon is pretty easy to them. If it comes down to the decision between Gentoo and Linux Mint this, of course, isn't true anymore, since Gentoo is way to complex for a beginner to understand.
Tl;dr: This is only true if you apply this to different distros with the same complexity(e.g. Pop_OS! or Linux Mint).
On the other hand, for someone just learning to use computer (ie. a child), GNOME in it's simplicity would be just great.
I feel like we've all been accustomed to the dumpster fire that is Windows, and selecting a DE that resembles it. GNOME feels and looks more like Android or iOS that have proven to be easy to learn from ground up and it still manages to offer a great desktop experience even if limited in customization many more advanced users want.
That's absolutely true. Windows managed to burn into our minds, that we have to look up how to install every single software.